Neurotrophic factors in Alzheimer’s disease: role of axonal transport
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چکیده
منابع مشابه
Neurotrophic factors in Alzheimer’s disease: role of axonal transport
Neurotrophic factors (NTF) are small, versatile proteins that maintain survival and function to specific neuronal populations. In general, the axonal transport of NTF is important as not all of them are synthesized at the site of its action. Nerve growth factor (NGF), for instance, is produced in the neocortex and the hippocampus and then retrogradely transported to the cholinergic neurons of t...
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Neurotrophins are growth factors with crucial roles in neural pathophysiology. These mediators functionally modulate nociceptive fibers, and changes in neurotrophins expression have been correlated with early loss of nociception in leprosy. This study investigated the expression of NGF, BDNF, and NT3 in dermal nerves of leprosy patients. Characterization of Remak bundles was achieved by p75(NTR...
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ژورنال
عنوان ژورنال: Genes, Brain and Behavior
سال: 2008
ISSN: 1601-1848,1601-183X
DOI: 10.1111/j.1601-183x.2007.00378.x